TO COMPARE THE EFFECTIVENESS OF KETOROLAC TROMETHAMINE AND DEXAMETHASONE WHEN USED AS FINAL IRRIGANT AFTER PULPECTOMY IN REDUCTION OF POST TREATMENT ENDODONTIC PAIN IN CHILDREN AGED 7 - 9 YEARS A RANDOMISED CONTROLLED CLINICAL TRIAL

COMPARATIVE EVALUATION OF THE EFFECTIVENESS OF KETOROLAC TROMETHAMINE AND DEXAMETHASONE IRRIGATION ON POST TREATMENT ENDODONTIC PAIN IN CHILDREN AGED 7 to 9 YEARS OF AGE: A RANDOMIZED CONTROL TRIAL - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075476

Enrollment

Registered

2024-10-17

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis Health Condition 2: B950- Streptococcus, group A, as the cause of diseases classified elsewhere

Interventions

Intervention1: KETOROLAC TROMETHAMINE AND DEXAMETHASONE : After cleaning and shaping, the canals will be dried in groups one and two. Ketorolac tromethamine (0.5 mg/ml) and dexamethasone (0.5 mg/ml) w

Eligibility

Inclusion criteria

Inclusion criteria: Medically fit children aged between 7 to 9 years • Children who are mentally capable of communication and those who can follow the instructions and be able to interpret the pain perception appropriately • Patients undergoing root canal treatment of primary mandibular teeth • All the patients who will report moderate to severe pain of continuous or nocturnal, radiating, or throbbing pain • Teeth responding to the cold sensibility test with exaggerated pain

Exclusion criteria

Exclusion criteria: 1. Patients with acute signs and symptoms requiring emergency treatment, with previous painful dental experience, and who are medically compromised 2. Grossly decayed teeth 3. History of any post-traumatic stress disorders or specific phobias related to dental settings 4. History of systemic mental or physical disorders 5. Restored, root fractures, periapical pathology, variations in roots 6. Cardiac patients 7. Patients taking medication 3 days prior

Design outcomes

Primary

Measure	Time frame
FINAL IRRIGATION WITH KETOROLAC TROMETHAMINE AND DEXAMETHASONE RESULTED IN LESS POST TREATMENT ENDODONTIC PAIN AND REDUCED THE NEED FOR TAKING ANALGESIC AFTER TREATMENTTimepoint: AFTER FINAL IRRIGATION DONE USING KETOROLAC TROMETHAMINE AND DEXAMETHASONE, POST TREATMENT ENDODONTIC PAIN WAS REDUCED SIGNIFICANTLY, AND THE NEED FOR TAKING ANALGESICS FOR POST TREATMENT ENDODONTIC PAIN WAS ALSO REDUCED	—

Secondary

Measure	Time frame
FINAL IRRIGATION WITH KETOROLAC TROMETHAMINE AND DEXAMETHASONE RESULTED IN NO REDUCTION OF POST TREATMENT ENDODONTIC PAIN AND THE PATIENT NEEDED ANALGESICS TO RELIEVE PAINTimepoint: EVEN AFTER USING KETOROLAC TROMETHAMINE AND DEXAMETHASONE AS THE FINAL IRRIGANTS, THERE WAS NO REDUCTION IN POST TREATMENT ENDODONTIC PAIN AND PATIENT NEEDED TO TAKE ANALGESICS TO RELIEVE PAIN	—

Countries

India

Contacts

Public ContactDr. Arjun Desani

Pacific Dental College and Hospital

pedodinesh2003@yahoo.co.in9414158235

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026