how effective and safe different doses of dexmedetomidine are when combined with ropivacaine, a pain-relief medication, given before surgery in the lower back area.

Comparison of efficacy and safety of different doses of dexmedetomidine combined with ropivacaine for caudal block in lumbosacral surgeries a prospective randomized controlled study - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075374

Enrollment

Registered

2024-10-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M45-M49- Spondylopathies

Interventions

Intervention1: Dexmedetornidine 2mcg/kg: Caudal block with dexmedetomidine 2mcg/ kg and ropivacaine under USG guidance Control Intervention1: Dexmedetomidine 1mcg/kg: Caudal block with dexmedetomidine

Eligibility

Inclusion criteria

Inclusion criteria: Patient scheduled for lumbosacral spine surgery Patient aged between 18years to 65years Patient with ASA grades 1 and 2 with both the sexes

Exclusion criteria

Exclusion criteria: Patient not willing to consent Patients with coexisting diseases like uncontrolled hypertension, diabetes, asthma, history of MI, CAD, etc Patients with preoperative opioid consumption Patients who underwent a previous lumbar spine surgery Patients with contraindications to regional anesthesia like the history of coagulopathies, preexisting neurologic deficit, active infection at the site of injection,etc Patients with hypersensitive to ropivacaine and dexmedetomidine Any lumbosacral anamoly Surgery exceeding more than 5hours

Design outcomes

Primary

Measure	Time frame
1. To evaluate and compare the analgesic effect of caudal epidural injection of different doses of dexmedetomidine with ropivacaine postoperatively Timepoint: Intraoperative and postoperative period	—

Secondary

Measure	Time frame
1.assess the hemodynamic effects of dexmedetomidine intraoperatively 2. To see the incidence of adverse effects between the two dosesTimepoint: Intraoperative and postoperative period	—

Countries

India

Contacts

Public ContactDr Rashmi Dubey

AIIMS RAIPUR

drrashmi1993@gmail.com8839829867

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026