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To compare Dexamethasone and Prednisolone in acute attack of bronchial asthma in children

Comparison of oral Dexamethasone and Prednisolone in Acute Bronchial Asthma: A Randomized Controlled Trial - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075351
Enrollment
82
Registered
2024-10-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J459- Other and unspecified asthma

Interventions

Intervention1: Dexamethasone: 0.6 mg/kg/day, max dose 15 mg, for 2 days, per oral Control Intervention1: Prednisolone: 2 mg/Kg/day, maximum dose 60 mg, for 5 days, , per oral

Sponsors

Department of Pediatrics Government Multi specialty hospital Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children between the ages of 2-12 years hospitalized with at least one previous exacerbation of wheeze or a known case of asthma.

Exclusion criteria

Exclusion criteria: 1. Contraindication for use of dexamethasone or prednisolone. 2. Significant medical comorbidity: Congenital and acquired heart disease, chronic lung disease, tuberculosis, cholestatic jaundice. 3. Life threatening exacerbation requiring PICU admissions. 4. Children already enrolled in the study and presenting within 60 days of discharge from hospital.

Design outcomes

Primary

MeasureTime frame
Comparison of improvement in PRAM scoreTimepoint: At admission, 12 hours, 24 hours

Secondary

MeasureTime frame
Comparison of length of hospital stay between 2 groups.Timepoint: 0 to 14 days;Comparison of recurrence of symptom.Timepoint: on day 7 after discharge;Need for additional steroid in dexamethasone group.Timepoint: within 24 hours

Countries

India

Contacts

Public ContactDr Neeraj Dhawan

Government Multi specialty Hospital, sector 16 , Chandigarh

ndhawan_6144@yahoo.com9815629496

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026