Comparing benifits of adding Dexamathasone versus Dexmeditomidine with Ropivacaine for pain control after breast removal surgeries

Dexamethasone versus Dexmeditomidine as an adjunct to Ropivacaine in Serratus Anterior Plane Block for patients undergoing Modified Radical Mastectomy - A Prospective Randomized Clinical study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075350

Enrollment

Registered

2024-10-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Dexamethasone as an adjunct to Ropivacaine in Serratus Anterior Plane Block for patients undergoing Modified Radical Mastectomy: Group A - Serratus Anterior Plane Block with 0.375% Ropi

Eligibility

Inclusion criteria

Inclusion criteria: Breast carcinoma patients undergoing Modified Radical Mastectomy under general Anaesthesia ASA status 1 &2 Patients who consented to the study

Exclusion criteria

Exclusion criteria: Patients who did not consent Preexisting bleeding disorders Coagulation disorders Morbid obesity Local inflammation Study drug allergy Patient with severe chest wall deformity.

Design outcomes

Primary

Measure	Time frame
Time to first rescue analgesia in minutes( defined as time from arrival in the postoperative recovery room to administration to first rescue analgesia )Timepoint: assessment after arrival in the postoperative recovery room and at 1,2,6,12,24 hrs after surgery	—

Secondary

Measure	Time frame
1.VAS pain score at 1,2,6,12 and 24 hours at rest (supine position ) and during activity (and on 90 degrees abduction of arm ipsilateral to the side of surgery ) 2. Total perioperative analgesic consumption (intraoperative fentanyl consumption + diclofenac and tramadol consumption post operatively 3. Monitoring of hemodynamic parametersTimepoint: 1. VAS pain scores at 1,2,6,12 and 24 hours at rest (supine position ) and during activity (defined as changing position supine to sitting 2.24 hours postoperatively 3. 24 hours postoperatively	—

Measure

Time frame

1.VAS pain score at 1,2,6,12 and 24 hours at rest (supine position ) and during activity (and on 90 degrees abduction of arm ipsilateral to the side of surgery ) 2. Total perioperative analgesic consumption (intraoperative fentanyl consumption + diclofenac and tramadol consumption post operatively 3. Monitoring of hemodynamic parametersTimepoint: 1. VAS pain scores at 1,2,6,12 and 24 hours at rest (supine position ) and during activity (defined as changing position supine to sitting 2.24 hours postoperatively 3. 24 hours postoperatively

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Countries

India

Contacts

Public ContactDr Harish Kumar

All India Institute Of Medical Sciences ,Bhopal

harishcmckol@gmail.com9471300943

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026