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To know the benefits of different fluids (normal saline and ringers lactate) in pediatric patients with shock.

To study the effectiveness of normal saline vs ringers lactate as resuscitative fluids in pediatric patients with shock . - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075328
Enrollment
26
Registered
2024-10-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I998- Other disorder of circulatory system

Interventions

Intervention1: RINGER LACTATE: WE WILLASSESS PATIENTS IN SHOCK AND WE WILL RANDOMLY INFUSE RINGER LACTATE AS A CHOICE OF FLUID Control Intervention1: NORMAL SALINE AND RINGER LACTATE: WE WILL ASSESS P

Sponsors

Dr Fatima Huda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: children included in the study which are more than 1 month upto 18 years of life presenting with shock requiring fluids resuscitation in casualty , ward or picu .

Exclusion criteria

Exclusion criteria: 1) patients who have been diagnosed with diabetic ketoacidosis 2) patients who have been diagnosed with chronic kidney diseases 3) for patients with inborn errors of metabolism 4) children undergoing chemotherapy

Design outcomes

Primary

MeasureTime frame
Primary objective : to compare level of acidosis (ph and bicarbonate ) in children with shock receiving ringer lactate or normal saline as resuscitative fluid. Timepoint: assessment will be at 0 hours ( i.e before administration of iv fluid as normal saline or ringers lactate ), 6 hours , 12 hours and 24 hours after administration of iv fluid as bolus .

Secondary

MeasureTime frame
Secondary objective : to compare: 1) metabolic response : electrolytes (sodium, chloride ,potassium) lactate, renal function tests 2) hemodynamic response :heart rate , blood pressure 3) inflammatory markers : CRP Timepoint: Assessed from time of admission to 72 hours of intervention

Countries

India

Contacts

Public Contactdr vinod ingale

MGM MEDICAL COLLEGE AND HOSPIAL

dr.vinodingale@gmail.com9823231421

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026