Health Condition 1: I998- Other disorder of circulatory system
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: children included in the study which are more than 1 month upto 18 years of life presenting with shock requiring fluids resuscitation in casualty , ward or picu .
Exclusion criteria
Exclusion criteria: 1) patients who have been diagnosed with diabetic ketoacidosis 2) patients who have been diagnosed with chronic kidney diseases 3) for patients with inborn errors of metabolism 4) children undergoing chemotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary objective : to compare level of acidosis (ph and bicarbonate ) in children with shock receiving ringer lactate or normal saline as resuscitative fluid. Timepoint: assessment will be at 0 hours ( i.e before administration of iv fluid as normal saline or ringers lactate ), 6 hours , 12 hours and 24 hours after administration of iv fluid as bolus . | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary objective : to compare: 1) metabolic response : electrolytes (sodium, chloride ,potassium) lactate, renal function tests 2) hemodynamic response :heart rate , blood pressure 3) inflammatory markers : CRP Timepoint: Assessed from time of admission to 72 hours of intervention | — |
Countries
India
Contacts
MGM MEDICAL COLLEGE AND HOSPIAL