Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA Grade I & II 2.Elective Caesarean Section 3.Patient willing to participate in the study 4.Patient with no history of neurological diseases 5.Patient With no history of allergy to Opioids, antiemetics and local anaesthetics.
Exclusion criteria
Exclusion criteria: 1.Patient not willing to participate in the study 2.ASA Grade III & IV 3.Emergency Surgery (Hemodynamic Compromise) 4.Contraindication to Spinal Anaesthesia 5.Patient With history of allergy to Opioids, antiemetics and local anaesthetics. 6.Pre-existing Dermatological Condition causing Pruritus at time of surgery 7.History of Respiratory disease, Cardiac disease, Neurological disease, Psychiatry disorder, Bleeding diathesis. 8.History of substance abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To Compare the efficacy of prophylactic Intravenous Ondansetron and Subcutaneous Naloxone in prevention of Intrathecal Morphine Induced Pruritus and Post-Operative nausea and vomiting.Timepoint: 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To elicit the incidence of pruritus & post-operative nausea & vomiting following Intrathecal Morphine in patients undergoing Caesarean sectionTimepoint: 24 hours;To find out the variation with those who received prophylactic Intravenous Ondansetron & Subcutaneous Naloxone especially in terms of post-operative analgesia durationTimepoint: 24 hours | — |
Countries
India
Contacts
Director, Institute of Anaesthesiology, Madurai medical college