Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intravenous infusion of Dexmedetomidine 0.5 mcg/kg: Intravenous infusion of Dexmedetomidine 0.5 mcg/kg over 10 minutes, just 10 minutes prior to skin closure
Control Intervention1: In
Sponsors
Smt Bhikiben Kanjibhai Shah Medical Institute and Research Cen
Eligibility
Inclusion criteria
Inclusion criteria: Patients willing to sign informed consent Male or Female patients between 18 to 65 years of age Patients belonging to American Society of Anesthesiologists(ASA) physical status I & II Patients posted for elective surgeries under general anesthesia.
Exclusion criteria
Exclusion criteria: Patients unwilling to participate in study. Patients with Body Mass Index more than 29 Kg per m square Patient with arrhythmias Pregnancy and lactating women Patients belonging to American Society of Anesthesiologists (ASA) III and above.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study haemodynamics and respiratory response during extubation.Timepoint: Preoperative After test drug administration After reversal During extubation After extubation At 1 min At 2 min At 3 min At 4 min At 5 min At 15 min At 30 min At 45 min At 60 min At 75 min At 90 min At 105 min At 120 min | — |
Secondary
| Measure | Time frame |
|---|---|
| To study sedation score after extubation or any side effects.Timepoint: Ramsay sedation score (RSS) will be recorded every 5minutes for 30 minutes and then every 30 minutes till 120 minutes. | — |
Countries
India
Contacts
Public ContactDr Tejash Sharma
Smt. Bhikiben Kanjibhai Shah Medical Institute and Research Centre
Outcome results
None listed