Health Condition 1: C14- Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: Standard standard Intensity Modulated Radiotherapy without dose constraints to DARS: Dysphagia optimised Intensity Modulated Radiotherapy with dose constraints to DARS
Intervention2: dy
Sponsors
Dr Prachi Upadhyay
Eligibility
Inclusion criteria
Inclusion criteria: Histologically proven non-metastatic oro-larynopharyngeal carcinoma, Karnofsky performance score more than 70 , normal haemogram, renal function tests, liver function tests and those who can follow and understand study related advice and are willing to give consent.
Exclusion criteria
Exclusion criteria: patient with prior or synchronous malignancy, prior treated with radiotherapy, metastatic oro-larynopharngeal carcinoma, patient underwent surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine whether reducing the dose to dysphagia aspiration related structures with dysphagia optimized intensity modulated radiotherapy (do-IMRT) will improve in long term swallowing function without compromising any tumor control or disease specific survival.Timepoint: 3 years | — |
Secondary
| Measure | Time frame |
|---|---|
| asses quality of life and factors associated with dysphagiaTimepoint: 3 years | — |
Countries
India
Contacts
Public ContactPrachi Upadhyay
SRMS IMS Hospital
Outcome results
None listed