Comparison of the effect of different combinations of Calcium Hydroxide as intra canal medicament on pain after the treatment in patients with symptomatic apical periodontitis.

Effect of Various Calcium Hydroxide Combinations as Intracanal medicament for Managing Post-Operative Pain in Symptomatic Apical Periodontitis Cases: A Double Blinded Study - NIL

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075265

Enrollment

Registered

2024-10-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: calcium hydroxide mixed with lidocaine as vehicle: Root canal treatment will be initiated under local anesthesia and rubber dam isolation. Working length will be established 1mm from ra

Eligibility

Inclusion criteria

Inclusion criteria: Mandibular molar teeth with symptomatic apical periodontitis with either irreversible pulpitis or necrotic pulp.Patients with preoperative pain on percussion with 50 mm or above on a visual analogue scale (VAS) scale Age 18-65 years. Teeth with PAI scores 1 and 2 described by Orstavik et al.

Exclusion criteria

Exclusion criteria: Patients on preoperative analgesics and antibiotics within past month. Presence of periodontal pockets more than 3 mm, sinus tract or swelling in the associated tooth Severely damaged teeth; teeth with root resorption; root fracture or ankylosis, bruxism. Root canal treated tooth Immunocompromised patients, pregnant and lactating mothers Patients who are older than 65 years old

Design outcomes

Primary

Measure	Time frame
The purpose of this study is to compare and evaluate pain reduction in patients with apical periodontitis using different combinations of calcium hydroxide with saline, lidocaine and dexamethasone.Timepoint: after every 24 hours for one week	—

Secondary

Measure	Time frame
to find any difference in pain reduction on using different vehicles with calcium hydroxide as intra canal medicaments.Timepoint: at 2 months	—

Countries

India

Contacts

Public ContactDr. ROHIT KOCHHAR

I.T.S. DENTAL COLLEGE, Greater Noida

hod.cons.gn@its.edu.in9810034451

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026