Pain management using transdermal Diclofenac, Ketoprofen and Lidocaine patch for patients undergoing modified radical mastectomy

To compare the efficacy of transdermal diclofenac, ketoprofen and lidocaine patch in post operative pain outcome in modified radical mastectomy patients and consumption of opioid in first 24 hours via patient controlled analgesia pump - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075264

Enrollment

Registered

2024-10-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site Health Condition 2: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Lidocaine Patch: GROUP L- Lignocaine Transdermal Patch Dose- 350mg Frequency- applied 1 hour prior to surgery and changed after 12 hour. Duration of action of one patch is 12 hours Cont

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing modified radical mastectomy Patients giving written consent ASA 1, 2 and 3

Exclusion criteria

Exclusion criteria: Patients operated for benign breast disease Patients undergoing repeat surgery or reconstructive breast surgery Allergic to Diclofenac, Ketoprofen or Lignocaine or any other drug used in the study

Design outcomes

Primary

Measure	Time frame
To compare the numerical rating score (NRS) score between diclofenac, ketoprofen and lidocaine patch groups and to evaluate the post operative 24 hour intravenous fentanyl consumption through Patient controlled analgesia pumpTimepoint: 1 hour pre induction to 24 hour post operative	—

Secondary

Measure	Time frame
To evaluate and document the complications and side effects of diclofenac, ketoprofen and lidocaine patch for post operative analgesia for 24 hours.Timepoint: 1 hour pre induction to 24 hour post operative	—

Countries

India

Contacts

Public ContactDr Sonali Mittal

Swami Rama Himalayan University

gurjeetkhurana@srhu.edu.in9410539190

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026