Health Condition 1: R99- Ill-defined and unknown cause of mortality
Conditions
Interventions
Intervention1: Topical application of 20 % nano curcumin mucoadhesive gel
systemic administration of elemental lycopene 6 mg and traces of oxidant
400 mg Vitamin E: 20% Nanocurcumin gel prepared in t
Sponsors
Dr Juhi Gupta
Eligibility
Inclusion criteria
Inclusion criteria: participant suffering with clinical presentation of oral potentially malignant disorders like leukoplakia, oral submucous fibrosis, oral lichen planus and fulfilling the clinical criteria for the diagnosis of the disease and willing to sign consent form for the trial.
Exclusion criteria
Exclusion criteria: patient with doubtful diagnosis and presence oral cancer. patient not willing to participate in the study. patient allergenic to curcumin. Patient on antidepressant or blood thinner
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to determine the improvement in the clinical sign and symptoms of potentially malignant disorders using topical application of 20% nanocurcumin gel with systemic administration of capsule lycostar twice a day Capsule Evion once daily and compare the effect with topical application of triamcinolone 0.1% w/w with systemic administration of 6 mg of elemental lycopene.Timepoint: Evaluation of the patient at baseline and than at weekly interval for 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine which treatment regimen is more effective for the treatment of potentially malignant disorder with long term remissionTimepoint: 3 months follow up after the treatment is completed | — |
Countries
India
Contacts
Public ContactDr Juhi Gupta
Dr. Ziauddin Ahmad Dental College
Outcome results
None listed