Comparing the Effectiveness between human menopausal gonadotropin drug and recombianant(genetically engineered) drug by assessing the oocyte quality in women undergoing in vitro fertilisation

Comparing treatment efficacy between recombinant FSH LH and recombinant FSH Highly purified human menopausal gonadotropins(HMG) A Prospective randomized controlled study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075239

Enrollment

390

Registered

2024-10-14

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N979- Female infertility, unspecified

Interventions

Intervention1: Giving rFSH and rLH for ovarian stimulation: Inj pergoveris and Inj gonal - f is given to subfertile patients undergoing stimulation for a duration of 10-11 days via subcutaneous route

Eligibility

Inclusion criteria

Inclusion criteria: BMI 18-35 kg/m 2 Unexplained subfertility Male Factor subfertility

Exclusion criteria

Exclusion criteria: Oocyte donor patients Congenital uterine anomalies uncorrected septum Patient with endometriosis grade3&4 SOAT, Necrozoospermia

Design outcomes

Primary

Measure	Time frame
Quality of oocytes assessed on the day of oocyte pick upTimepoint: Following 10-11 days of stimulation, once the follicle reaches more than 18 mm, trigger injection is given to induce ovualtion and maturation of follicles. oocyte pickup done 35 hours after trigger injection. after oocyte pickup, following denudation quality of oocytesis assessed on the same day.	—

Secondary

Measure	Time frame
Oocyte maturity rate, ICSI normal fertilization rate, Blastocyst development rate, Clinical Pregnancy rateTimepoint: Oocyte maturity rate- on the same day as oocyte pick up day, ICSI normal fertilization rate- one day post pickup, Blastocyst development rate- day 5 after oocyte pickup, Clinical Pregnancy rate 4 weeks after embryo transfer.	—

Countries

India

Contacts

Public ContactArchana S

A4 Hospital and Fertility centre

drarchana@a4fertility.com9840861267

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026