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To compare the recovery from general anaesthesia in microlaryngeal surgery using rocuronium and sugammadex versus succinylcholine, cisatracurium and neostigmine in microlaryngeal surgery

Comparison of emergence from general anaesthesia in microlaryngeal surgery using rocuronium and sugammadex with succinylcholine, cisatracurium and neostigmine: a prospective randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075208
Enrollment
60
Registered
2024-10-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J958- Other intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified

Interventions

Intervention1: Rocuronium and Sugammadex group: Rocuronium (1.5mg/kg) intubation dose with maintenance dose of (0.15mg/kg) and reversal of sugammadex (2.0mg/kg). With the help of acceleromyography, ne

Sponsors

Prerna Nayan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 18 to 70 years, with ASA I to III undergoing elective MLS surgery.

Exclusion criteria

Exclusion criteria: 1. Difficult airway 2. Neuromuscular disorders that impair neuromuscular blockade 3. Significant renal dysfunction 4. History of malignant hyperthermia 5. History of allergies to narcotics, muscle relaxants or other medications used during anaesthesia 6. Pregnant and breastfeeding, post-natal patients or child-bearing age and 7. ASA 4 and above patients

Design outcomes

Primary

MeasureTime frame
To compare the emergence from general anesthesia between rocuronium and sugammadex with succinylcholine, cisatracurium and neostigmine among elective microlaryngeal surgeries in a tertiary care center in India during the year 2024.Timepoint: 1 hour

Secondary

MeasureTime frame
To assess the surgical conditions during the microlaryngeal surgeries. To assess the adequacy of muscle relaxant during intubation conditions. To evaluate the possible intraoperative and immediate postoperative adverse events. Timepoint: 1 hour

Countries

India

Contacts

Public ContactSathish Kumar D

Christian Medical College

drsathish78@yahoo.com6369379259

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026