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Comparison of effects of dexamethasone and haloperidol Vs dexamethasone and amisulpride on postoperative nausea and vomiting in laproscopic cholecystectomy.

Comparison of effects of dexamethasone and haloperidol Vs dexamethasone and amisulpride on postoperative nausea and vomiting in laproscopic cholecystectomy Randomised, controlled, double blinded study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075204
Enrollment
96
Registered
2024-10-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K808- Other cholelithiasis

Interventions

Intervention1: i/v dexamethasone: Patients of this group will receive Dexamethasone 8mg in 2ml and Normal Saline 2 ml I/V just before induction of anesthesia. Control Intervention1: i/v haloperidol: P

Sponsors

Sharda Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective laproscopic Cholecystectomy under General Anaesthesia. 2. ASA class 1 and 2. 3. Age 18-60 years. 4. Patients having at least two of following risk factors of PONV i.e ( Female gender , Non smoker , Prior history of PONV or motion sickness , being expected to receive opioid analgesia.)

Exclusion criteria

Exclusion criteria: 1.Patient receiving steroids, analgesics, antiemetic, sedatives and antipsychotics 2.Patient with past history of chronic pain. 3.Patient having history of endocrine, cardiovascular, renal or CNS disease 4.Patient having GI, Hepatic, renal disease. 5.Patient allergic to study drugs. 6.BMI more then 30.

Design outcomes

Primary

MeasureTime frame
To compare the effects of dexamethasone and haloperidol vs dexamethasone and amisulpride in comparison of control group on the incidence of post operative nausea vomiting in patient of laproscopic cholecystectomy under GA. Timepoint: 24 Hrs.

Secondary

MeasureTime frame
a)To compare the PONV free period and requirement of rescue antiemetic in three groups b)To compare the sedation score and pain score in three groups . Timepoint: 24 hrs.

Countries

India

Contacts

Public ContactDR MAHENDERA KUMAR

School of Medical Sciences and Research

mahendra.kumar@sharda.ac.in8287188449

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026