Health Condition 1: D332- Benign neoplasm of brain, unspecified
Conditions
Interventions
Intervention1: Pregabalin: 150 mg each Given on night before and morning 2 hours before surgery with sips of water
Control Intervention1: placebo/vitamin capsules: Given on night before and morning 2
Sponsors
Nil
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients of either gender 2) Age 18–65 years 3) ASA class I, II 4) Patients with GCS 15 5) Scheduled for elective craniotomies for excision of brain tumors
Exclusion criteria
Exclusion criteria: 1)Allergy to study drugs and opioid dependence. 2)Patients undergoing emergency surgery. 3)Patients receiving chronic neuroleptics, tricyclic antidepressants, serotonin noradrenaline reuptake inhibitors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a]Total intra-operative opioid consumption b] Post-operative pain scores and rescue analgesia.Timepoint: a]Till 12 hours postoperative b]Till 12 hours postoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| a] Incidence of adverse effects of opioids like PONV, shivering. b] Incidence of emergence delirium and delayed recovery.Timepoint: a]Till 12 hours postoperative | — |
Countries
India
Contacts
Public ContactDr Monica Malhotra
AIIMS, RAIPUR
Outcome results
None listed