Comparing Autogenous Dentin graft and Xenograft for Socket preservation- A Randomized Controlled Clinical Trial

Clinical, Radiographic, Histological and Histomorphometric Analysis of Socket Preservation, Comparing Autogenous dentin graft and Xenograft following an Open Membrane Technique A Randomized Controlled Clinical Trial. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075171

Enrollment

Registered

2024-10-14

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K068- Other specified disorders of gingiva and edentulous alveolar ridge Health Condition 2: K068- Other specified disorders of gingiva and edentulous alveolar ridge

Interventions

Intervention1: Autogenous dentin graft: The extracted tooth will be placed in the dentin crusher (KometaBio grinding device).The Crushed dentin particles will be collected and placed in the Dentin cle

Eligibility

Inclusion criteria

Inclusion criteria: Age = 20 years Type I extraction socket morphology Healthy or stable periodontal status Teeth that is indicated for extraction due to caries, fracture, endodontic failure Need for implant restoration at the site of extraction

Exclusion criteria

Exclusion criteria: Medical and general contraindications for the surgical procedure, expressed by ASA score = III (Smeets, de Jong, & Abraham ?Inpijn, 1998) Patients with any systemic disorder known to interfere with periodontal treatment such as diabetes, coronary heart disease, Rheumatoid Arthritis, Rheumatic Fever, SLE, Malignancy, Respiratory diseases, Renal diseases, Other (e.g., autoimmune diseases, fungal infections, immunological deficiencies, etc.) Presence of periodontal disease, expressed by pocket probing depths of =4 mm and bleeding on probing (modified sulcus bleeding index score =2); Smoking Earlier treatment with radiotherapy to the head and neck region Pregnancy Post-extraction bony defect Patients on intramuscular or intravenous bisphosphonates Allergies or sensitivity to alginate, latex, collagen or acrylic

Design outcomes

Primary

Measure	Time frame
New bone formation - histological and histomorphometric analysis Horizontal ridge width and vertical bone height - Radiographic analysis Width of keratinized gingiva - Clinical analysis PROMS - Wound healing , Pain and patient satisfactionTimepoint: Histological , Histomorphometric and Radiographic , Clinical- Baseline, 4 months PROMs- 5 days and 1 month	—

Secondary

Measure	Time frame
New bone formation - histomorphometric analysis Width of keratinized gingiva - Clinical analysisTimepoint: Histomorphometric & Clinical- Baseline, 5 months	—

Countries

India

Contacts

Public ContactS Poojyashree

Sri Ramachandra Institute Of Higher Education and Reseach.

muthukumars@sriramachandra.edu.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026