To compare heamodynamic stability of Bolus versus fractionated injection of hyperbaric bupivacaine in spinal anaesthesia among patients undergoing femur fracture surgery

Efficacy of Bolus versus fractionated injection of hyperbaric bupivacaine in spinal anaesthesia among patients undergoing femur fracture surgery: A randomized control trial - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075154

Enrollment

Registered

2024-10-11

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: M958- Other specified acquired deformities of musculoskeletal system Health Condition 3: W19- Unspecified fall

Interventions

Intervention1: fractionated injection of hyperbaric bupivacaine in spinal anaesthesia among patients undergoing femur fracture surgery: 25 patients will be given spinal anaesthesia for the femur fract

Eligibility

Inclusion criteria

Inclusion criteria: 1. Elective Femur fracture surgeries under Spinal Anaesthesia. 2. Patients between age 60-80 years 3. ASA grade I, II and III.

Exclusion criteria

Exclusion criteria: 1. Subjects with suspected inability to comply with the study procedure. 2. Known allergy to drug study. 3. History of liver Renal and Cardiac disease.

Design outcomes

Primary

Measure	Time frame
TO COMPARE HEAMODYNAMIC PARAMETERS (HEART RATE AND MEAN ARTERIAL BLOOD PRESSURE) BETWEEN THE TWO STUDY GROUPS.Timepoint: Intra Op Monitoring of Heart Rate Blood pressure and Mean arterial Pressure every 3 minutes for first 20 minutes. Thereafter every 10 minutes till regression of sensory block to L1 level	—

Secondary

Measure	Time frame
Intra Op Monitoring of motor & sensory characteristicsTimepoint: Level of sensory block was checked every 3 minutes till peak sensory level that is two consecutive reading at the same dermatomal level will be achived. Thereafter sensory block will be tested every 20 min till the block regression to L1 level.Motor blockade will be checked every 3 minutes for first 20 minutesfrom start of surgery & every 10 minutes thereafter.	—

Measure

Time frame

Intra Op Monitoring of motor & sensory characteristicsTimepoint: Level of sensory block was checked every 3 minutes till peak sensory level that is two consecutive reading at the same dermatomal level will be achived. Thereafter sensory block will be tested every 20 min till the block regression to L1 level.Motor blockade will be checked every 3 minutes for first 20 minutesfrom start of surgery & every 10 minutes thereafter.

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Countries

India

Contacts

Public ContactDr V M Sasturkar

MGM Medical College and Hospital Aurangabad

vasantikelkar70@gmail.com9370668196

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026