Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: Contralateral neck dissection (levels 1b and 2a): In patients undergoing surgery for oral cancers from November 01,2024 till October 31 2026, those who fit the inclusion criteria will b
Sponsors
Dr.Jino JL
Eligibility
Inclusion criteria
Inclusion criteria: 1) Resectable, locally advanced oral SCC (AJCC 8th Edition TNM Stage IVA and IVB), which does not involve or cross the midline—clinical tumor stage T4a or T4b disease in the gingivobuccal complex and T3 tumors of the tongue and floor of the mouth. 2) Ipsilateral nodal involvement with extra-nodal extension (N3b) 3) Biopsy: Poorly differentiated tumor grade 4) No clinical or radiological evidence of contralateral nodal metastasis
Exclusion criteria
Exclusion criteria: 1) Past history of treatment for head and neck cancer 2) Borderline resectable, unresectable, inoperable or metastatic disease at presentation 3) Clinical or radiological evidence of contralateral nodal metastasis 4) Recurrent oral cancer planned for salvage surgery 5) Tumor involving or crossing the midline 6) T1, T2 disease 7) Multiple or synchronous primary tumors in the head and neck 8) Under 18 years of age or over 90 years of age, or who are pregnant or otherwise vulnerable
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of contralateral nodal metastasis in histopathological specimenTimepoint: Post surgery, second week - when the histopathological report comes, Post surgery follow-up at 3months, 6months. 9 months and one year | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)To correlate the incidence of contralateral nodal metastasis with other clinicopathological adverse prognostic factors in oral squamous cell carcinoma. 2)To develop a statistical model incorporating predictive factors for contralateral nodal metastasis to guide the need for contralateral neck dissection for oral squamous cell carcinoma. Timepoint: Post operative period;Contralateral nodal recurrence rateTimepoint: one year | — |
Countries
India
Contacts
Public ContactJino JL
Christian medical college and hospital
Outcome results
None listed