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Comparison of effect of ultrasound guided median nerve release through hydrodissection using dextrose and normal saline for treatment of carpal tunnel syndrome

Comparison of ultrasound guided hydrodissection with dextrose versus normal saline for treatment of carpal tunnel syndrome: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075028
Enrollment
34
Registered
2024-10-10
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G560- Carpal tunnel syndrome

Interventions

Intervention1: Hydrodissection using 5%dextrose: Median nerve will be identified using USG. 5cc to 10 cc of 5% dextrose (depending upon the completeness of the laminar separation) will be slowly inje

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients having NCS proven carpal tunnel syndrome with persistent symptoms not resolving after 6-8 weeks of medications or splinting referred from orthopaedics department for hydrodissection

Exclusion criteria

Exclusion criteria: : Patients with other neurological causes like polyneuropathies, thoracic outlet syndrome, cervical radiculopathy; secondary causes like ganglion cysts, accessory muscles; received prior steroid injection / carpal tunnel release surgery ; thenar atrophy; local site infection , history of Colles’ fracture; uncontrolled diabetes / diabetic neuropathy , uncontrolled hypothyroidism or bleeding diathesis

Design outcomes

Primary

MeasureTime frame
Comparison of improvement in BCTQ(SSS), BCTQ (FSS), VAS and CSA of median nerve from pre procedure to post procedure in both groups.Timepoint: At 1 month , 3 month and wherever possible 6 months

Secondary

MeasureTime frame
1. Change from baseline of BCTQ (SSS), BCTQ (FSS) and VAS after ultrasound guided hydrodissection with 5% dextrose . 2. Change from baseline of BCTQ (SSS), BCTQ (FSS) and VAS after ultrasound guided hydrodissection with normal saline . 3. Change from baseline of cross-sectional area (CSA) of the median nerve using ultrasound in both groups. 4. Comparison of complications between the two injectate groups (expressed as %). Timepoint: At 1 month , 3 month and wherever possible 6 months

Countries

India

Contacts

Public ContactDr Anupama Tandon

Department of Radiodiagnosis, UCMS and GTB Hospital, Dilshad Garden, Delhi

anupamatandon@hotmail.com8585977903

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026