Evaluation of efficacy of neostigmine vs sugammadex for reversal of vecuronium induced neuromuscular blockage in patients scheduled for elective surgeries under general anaesthesia: Prospective, double blind randomized controlled study.

Evaluation of efficacy of neostigmine vs sugammadex for reversal of vecuronium induced neuromuscular blockage in patients scheduled for elective surgeries under general anaesthesia: Prospective, double blind randomized controlled study. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/075012

Enrollment

Registered

2024-10-09

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: inj. sugammadex: giving inj. sugammadex 2mg/kg in 10ml normal saline for reversal of neuromuscular blockage. Control Intervention1: inj. neostigmine with inj. glycopyrolate: Patient wil

Eligibility

Inclusion criteria

Inclusion criteria: Age : 18-60 years ASA grade I-III. Patient scheduled for a surgical procedure under general anaesthesia in a supine position requiring tracheal intubation.

Exclusion criteria

Exclusion criteria: Difficult airway Known neuromuscular disorders Significant hepatic and/or renal disorders Known family history of malignant hyperthermia Allergies to drug Administration of any medication interfering with NMBDs Pregnant females or lactating mothers

Design outcomes

Primary

Measure	Time frame
To compare recovery time from vecuronium-induced neuromuscular blockage in both the groups. To compare the haemodynamic changes(Blood pressure, Pulse rate and SpO2) in both the groups. Timepoint: 15 months	—

Secondary

Measure	Time frame
To compare the side effect and complication, if any in both the groups. Timepoint: 15 months	—

Countries

India

Contacts

Public ContactDr Shilpa Doshi

Department of Anaesthesiology Government Medical College Bhavnagar

drshilpadoshi@yahoo.in9428810763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026