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norepinephrine and phenylephrine infusion for controlling spinal anaesthesia induced hypotension in caesarean section

a comparative study of prophylactic norepinephrine and phenylephrine infusion for controlling spinal anaesthesia induced hypotension in parturients undergoing lower section caesarean section-randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/075003
Enrollment
104
Registered
2024-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: administration of intravenous infusion of 150 mcg/hr of norepinephrine: Study participants will be randomized into 2 groups. One intervention group receiving an intravenous infusion of

Sponsors

Joydeepa Das
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age group 18 to 45 years undergoing elective caesarean section Patients with American Society of Anaesthesiologists (ASA) physical grade I or II

Exclusion criteria

Exclusion criteria: history of allergy to local anesthetic drug and study drugs local site infection spinal deformity parturients with PET or any hypertensive disorder bleeding disorders cardiac, respiratory diseases, kidney disorders, neurological deficit

Design outcomes

Primary

MeasureTime frame
occurence of hypotensionTimepoint: outcome will be continuosly recorded every 2 mins till 10mins then every 5 mins until the end of surgery and data will be assessed at the end of one year

Secondary

MeasureTime frame
Apgar score, umbilical vein blood gases record, hemodynamic changes, norepinephrine consumption, adverse effectsTimepoint: all outcomes will be continuously recorded every 2 mins till 10 mins and then every 5 mins until the end of surgery

Countries

India

Contacts

Public ContactDr T Hemjit Singh

Regional Institute of Medical Sciences

takhelhem@yahoo.com9436021445

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026