Skip to content

Opioid sparing anesthesia in laparoscopic gall bladder surgery using Dexmedetomidine

Comparison of analgesic efficacy of dexmedetomidine for opioid-sparing anesthesia with conventional opioid-based anesthesia for elective laparoscopic cholecystectomy: a prospective randomized controlled study. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/074979
Enrollment
78
Registered
2024-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Opioid sparing Anesthesia with Dexmedtomidine: One group of patients are given Dexmedetomidine infusion with loading dose 0.3mcg/kg for 10min at induction of anaesthesia, followed by 0.

Sponsors

Adarsh K P
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective laparoscopic cholecystectomy surgery Patients under ASA 1 and ASA2 class Baseline Heart rate more than 50beats per minute

Exclusion criteria

Exclusion criteria: Patients of ASA 3 and above Patient refusal Patients on betablocker drugs Patient with history of Cardiac arrhythmia Patients with deraged renal function Any history of allergy to any of study drugs Patients with history of bronchial asthma Patients at risk of aspiration Pregnant and lactating mothers

Design outcomes

Primary

MeasureTime frame
Total (intraoperative and postoperative) rescue Fentanyl usage for analgesia when using Dexmedetomidine infusion compared to conventional opioid based anesthesia.Timepoint: Total usage at 0hour post procedure total usage till 24hour post procedure

Secondary

MeasureTime frame
any complication associated with dexmedetomidine or opioidTimepoint: intraoperative & post operative period till 24 hours;incidence of postoperative nausea & vomitingTimepoint: post operative period till 24 hours;time to extubation and eye opening to callTimepoint: intraoperative

Countries

India

Contacts

Public ContactDr Renita M Pinto

Aster CMI Hospital

drarun.v@asterhospital.com9496471379

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026