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A Randomised Control study : Clomiphene Citrate vs Tamoxifen for Ovulation in Anovulatory infertile women

A RANDOMIZED CONTROL TRIAL TO COMPARE EFFECTIVENESS OF CLOMIPHENE CITRATE VS TAMOXIFEN IN INDUCTION OF OVULATION IN ANOVULATORY INFERTILE WOMEN - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/074977
Enrollment
62
Registered
2024-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N970- Female infertility associated withanovulation

Interventions

Intervention1: Administration of Tablet Clomiphene Citrate: Administration of Tablet Clomiphene Citrate 50mg per orally from Day 2 of menstrual cycle till day 7 of cycle Dose is escalated to 100mg a

Sponsors

Dr P Santhosh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age: 18 - 35 years. 2. Body mass index (BMI): 18 - 30 kg/m2. 3. Patients with normogonadotropichypogonadism (WHO type 2). 4. Normal semen analysis of the husband. 5. Normal serum Prolactin 6.Consenting to participate in the study

Exclusion criteria

Exclusion criteria: 1.Thyroid dysfunction, active liver diseases. 2. Local diseases as endometriosis, ovarian tumors, hydro- or pyosalpinx etc. 3. Patients with previous history of Ovulation induction. 4. Patients with previous history of ovarian drilling. 5.Any Medical complications 6.Any Obstetrical complications 7. Any contraindication for Tab Clomiphene citrate or Tab Tamoxifen.

Design outcomes

Primary

MeasureTime frame
Incidence of ovulationTimepoint: Follicular scan from Day 11 of menstrual cycle till Day14

Secondary

MeasureTime frame
1 Estimation of Endometrial thickness 2 Incidence of Pregnancy 3 Outcome of PregnancyTimepoint: 1 Estimation of Endometrial thickness from Day 11 to Day 14 of menstrual cycle 2 Urine Pregnancy Test on 28 day of menstrual cycle 3 Outcome of Pregnancy at 14 weeks of gestation

Countries

India

Contacts

Public ContactDr P Santhosh

Karnataka Medical College and Research Institute Vidyanagar Hubballi

omkabadi@gmail.com9448210579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026