Comparison of two sedative drugs (dexmeditomidine and remifentanil) with respect to vital signs and recovery time in patients who undergo a camera test of the windpipe (rigid bronchoscopy).

A Comparison between Dexmedetomidine and Remifentanil for rigid Bronchoscopic Pulmonary Procedures A Randomized Controlled Trial - NIL

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/074972

Enrollment

Registered

2024-10-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J984- Other disorders of lung

Interventions

Intervention1: Dexmeditomidine group: Dexmeditomidine (0.5mcg/kg) for 10 min, f/b dexmedetomidine infusion (0.5-1.4mcg/kg/hour)will be given before and during bronchoscopy. The duration for which the

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 18 to 80 years of age and American Society of Anesthesiologists (ASA) Physical Status Class I, II and III. 2.Patients undergoing rigid bronchoscopic procedures. 3.Patients giving consent for the procedure.

Exclusion criteria

Exclusion criteria: 1. ASA - 4 AND 5 2. Severe renal, hepatic or heart failure 3. heart blocks 4.severe obesity 5. allergy to any medications 6.refusal to give consent 7.pregnancy 8.Procedure that takes more than 2 hours.

Design outcomes

Primary

Measure	Time frame
The change in hemodynamic variables between the groups during rigid bronchoscopy. Timepoint: Baseline, during rigid bronchoscopy, every 5minutes after that till bronchoscopy is complete. 5, 10, 15, 30 minutes, 1hour, 2 hours, 4 hours, and 6 hours postop	—

Secondary

Measure	Time frame
The time needed for patients to meet postanesthesia care unit discharge criteria (Aldrete score: 9) Timepoint: till 6hrs postop;nausea/vomitingTimepoint: till 6hrs postop;postop coughTimepoint: till 6hrs postop;time taken for BIS score to reach 80Timepoint: till 6hrs postop;Post-op Sore throatTimepoint: till 6hrs postop	—

Countries

India

Contacts

Public ContactDr Brajesh kumar Ratre

All India Institute Of Medical Sciences- New Delhi

brajesh.ratre@gmail.com8696156799

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026