Treatment of vitamin B12 deficiency in children

Low versus high oral dose of vitamin B12 for treatment of macrocytic anemia: a randomised controlled trial in a District hospital - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/074903

Enrollment

Registered

2024-10-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D519- Vitamin B12 deficiency anemia, unspecified

Interventions

Intervention1: Vitamin B12 lower dose: Less than 2yr. - 750µg More than 2yr. - 1000µg For 1 month Intervention2: Vit. B12 High dose: Higher dosage of vit. B12 Will be given Control Intervention1: Hig

Eligibility

Inclusion criteria

Inclusion criteria: All children between 2month to 12 years age with vit. B12 deficiency & symptoms will be included.

Exclusion criteria

Exclusion criteria: 1. Neurological symptoms other than infantile tremor syndrome. 2. Those who have received blood transfusion or vit. B12 therapy upto one month prior to admission

Design outcomes

Primary

Measure	Time frame
comparison of change in serum vitamin B12 level after treatment between 2 groups.Timepoint: At 4 weeks.	—

Secondary

Measure	Time frame
comparison of changes in level of hematological parameters between 2 groups.Timepoint: 1 month	—

Countries

India

Contacts

Public ContactDr Shashi Kiran Singh

Government Multi Speciality hospital-16 Chandigarh

singhshashikiran72@gmail.com9814735929

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026