Skip to content

To compare two inhalational agents and assess cognitive brain function in patients undergoing general anaesthesia

Comparative study of clinical effect of sevoflurane vs desflurane on cognitive brain function in patients undergoing surgery with general anaesthesia - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/074875
Enrollment
98
Registered
2024-10-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: R419- Unspecified symptoms and signs involving cognitive functions and awareness

Interventions

Intervention1: sevoflurane Inhalational agent: Inhalational sevoflurane 1-1.5% in combination with nitrous oxide 50% which coressponds to 1-1.8MAC will be maintained till the end of surgery Control I

Sponsors

G R Sukanya
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients willing to participate in the study. 2) Patients with ASA grade 1and 2 with normal cognitive function. 3)Patients undergoing surgery with General Anaesthesia

Exclusion criteria

Exclusion criteria: 1)Patients not willing for the study. 2) Patients with abnormal hepatic,neurological,pulmonary,psychiatry,cardiovascular function. 3) Patients who had already participated in another clinical trial. 4) Emergency cases.

Design outcomes

Primary

MeasureTime frame
changes in cognitive function outcome after using sevoflurane or desflurane in general anaesthesiaTimepoint: assessment of cognitive function immediate postop and 24 hours postoperative

Secondary

MeasureTime frame
to evaluate the incidence & risk factors of delirium & to evaluate the hemodynamic changes in the intraoperative periodTimepoint: delirium after extubation immediately ,after 6 hours & 24 hours respectively. hemodynamic status during the procedure

Countries

India

Contacts

Public ContactDr Veena Ganeriwal

Grant Medical College and JJ Hospital

veenaganeriwal@gmail.com9821300699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026