Health Condition 1: D330- Benign neoplasm of brain, supratentorial
Conditions
Interventions
Intervention1: fentanyl: Fentanyl infusion at1µg/kg/hr starting from induction till
closure of dura .
Control Intervention1: Dexmedetomidine: Dexmedetomidine infusion 0.5 µg/kg/hr from
induction till
Sponsors
Dr Bishnupriya Mohapatra
Eligibility
Inclusion criteria
Inclusion criteria: Patient belonging to ASA I,II,III Patients with pre operative GCS more than 14 Patient posted for elective supratentorial lesion
Exclusion criteria
Exclusion criteria: Patient posted for emergency craniotomy surgeries 3) Patient belonging to ASA IV and above 4) Patient with bradycardia (Heart rate <60 beats per minute) 5) Patient refusing to consent 6) Patient with chronic pain or on opioid medication 7) Patient with known allergy to study drugs 8) Patients with difficult airway
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare duration to first rescue analgesic requirement in post operative period in patients undergoing supratentorial craniotomy receiving opioid based anesthesia and those receiving opioid free anesthesiaTimepoint: To compare duration to first rescue analgesic requirement in post operative period in patients undergoing supratentorial craniotomy receiving opioid based anesthesia and those receiving opioid free anesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| compare quality of recovery (QoR- 15) scoreTimepoint: at 1, 6 ,12 , 24 hours post operatively and at discharge;incidence of side effects like bradycardia, tachycardia, hypotension , hypertension, post operative nausea vomiting , pruritus, respiratory depressionTimepoint: post operatively.;post operative pain at 1,2,4,6,12 and 24 hours post operatively.Timepoint: at 1,2,4,6,12 and 24 hours post operatively.;total dose of rescue analgesicTimepoint: post operatively.;total number of propofol bolusTimepoint: intra operatively. | — |
Countries
India
Contacts
Public ContactDr Sanjay Agrawal
AIIMS Rishikesh
Outcome results
None listed