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Eeffectiveness of Intravenous Versus Nebulized Ketamine-Dexmedetomidine Combination (Ketodex) in Awake Fiberoptic Intubationis compare.

Comparison of efficacy of Intravenous Versus Nebulized Ketamine-Dexmedetomidine Combination (Ketodex) in Awake Fiberoptic Intubation - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/074790
Enrollment
68
Registered
2024-10-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: Intravenous Ketamine 0.5mg/kg-Dexmedetomedine 1mcg/kg (Keto Dex): Intravenous Ketamine 0.5mg/kg, Dexmedetomidine(1mcg/kg)Keto Dex) in 20 ml of normal saline for 10 minutes,once,after s

Sponsors

Dr Shikha Jain
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with the ASA physical status I or II according to the American Society of Anesthesiologists (ASA)

Exclusion criteria

Exclusion criteria: 1. Patients who refuse or uncooperative such as those with mental retardation, lack of communication, blindness, and deafness were excluded from the study. 2. Patients who had coagulation disorders, respiratory or pulmonary disorders, pregnancy or full stomach, increased intracranial pressure or intraocular pressure, and emergency surgeries or allergy to the drug used in the study or with risk for regurgitation–aspiration were excluded from the study?

Design outcomes

Primary

MeasureTime frame
1. Difference in time (sec) taken to intubate the patients during Awake Fiberoptic Intubation in both the groups 2. Difference in the ease of intubation with the help of intubation score (vocal cord movement, limb movement, and cough) at the time of entry of tip of endotracheal tube through the glottis.? Timepoint: At the time of intubation

Secondary

MeasureTime frame
1.Difference in hemodynamic variables (Heart rate (HR), mean arterial pressure (MAP), and peripheral oxygen saturation (SpO2) in both the groups after starting the infusion every two minutes for 10 minutes. 2. Difference in Post-operative Patient satisfaction score & adverse effects after 24 hours post extubationTimepoint: 1.After starting the infusion every two minutes for 10 minutes 2. After 24 hours post extubation

Countries

India

Contacts

Public ContactDr Shikha Jain

AIIMS BHOPAL

Shikha.anaesth@aiimsbhopal.edu.in7987164388

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026