To Evaluate the Effectiveness of Repetitive Transcranial Magnetic Stimulation rTMS in augmenting patients with Treatment Resistant Depression

Effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS )as an augmenting agent in Treatment Resistant Depression - rTMSTRD

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/074777

Enrollment

Registered

2024-10-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F332- Major depressive disorder, recurrent severe without psychotic features Health Condition 2: F331- Major depressive disorder, recurrent, moderate

Interventions

Intervention1: repetitive Transcranial Magnetic Stimulation rTMS: 10Hz (120% MT) C3 40 pulses, 75 trains, inter-train interval 11 over 19 min 10 sessions over 2 weeks Control Intervention1: Sham group

Eligibility

Inclusion criteria

Inclusion criteria: no response to two antidepressant trials of six weeks each criteria for depression hamd score of more than eight

Exclusion criteria

Exclusion criteria: Psychotic Disorder Epilepsy Substance Abuse Metal Implants Pregnancy Recent Brain Surgery or Psychosurgery

Design outcomes

Primary

Measure	Time frame
improvement in scores of HAMD/HDRS, MADRS over 4 weeksTimepoint: 2 and 4 weeks post intervention	—

Secondary

Measure	Time frame
improvement in scores of PSQI and MOCA over 4 weeksTimepoint: 2 and 4 weeks post intervention	—

Countries

India

Contacts

Public ContactVishav Rakesh Damathia

ABVIMS and Dr. Ram Manohar Lohia Hospital

gautamsharma@dr.com9313231020

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026