A study to compare post-operative effect of skin infiltration of dexmedetomidine with ropivacaine versus dexamethasone with ropivacaine in midline neck surgery under general anaesthesia.

A comparative study of post-operative analgesic efficacy of 0.25 percentage ropivacaine with dexmedetomidine versus dexamethasone as an adjuvant in bilateral superficial cervical plexus block for midline neck surgery under general anaesthesia. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/074748

Enrollment

Registered

2024-10-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj.dexmedetomedine with ropivacaine: Inj.Dexmedetomedine 50 mcg as an adjuvant with 0.25percentage ropivacaine in bilateral superficial cervical plexus block under general anaesthesia

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients willing to participate in the studys. 2. Patients of ASA Grade I and II of either gender. 3. Patients undergoing elective midline neck surgeries under general anaesthesia 4. Age of patients 18-65 years.

Exclusion criteria

Exclusion criteria: 1 Patient refusal. 2 Patient not nil by mouth. 3 Patients with uncontrolled systemic disease like heart disease, liver disease, kidney disease. 4 Patients with anaemia, shock, septicaemia, uncontrolled hypertension. 5 Patients with bleeding and coagulation disorders 6 Infection at site 7 History of upper mediastinal irradication 8 Inability to tolerate general anaesthesia 9 Any neck metastasis 10 History of previous head and neck surgery 11 Hoarse and weak voice

Design outcomes

Primary

Measure	Time frame
To check post operative reduction in opioids requirement with drug 0.25% ropivacaine with dexmedetomidine versus dexamethasone as an adjuvant given in bilateral superficial cervical plexus block for midline neck surgery under general anaesthesia.Timepoint: Pain assessment every 2hrly post operatively from 0hr to 24hr.	—

Secondary

Measure	Time frame
Sedation score & any side effects.Timepoint: Post-operatively after extubation & then at 2 hourly till 24 hours.	—

Countries

India

Contacts

Public ContactDevendra Joshi

Smt. Bhikiben Kanjibhai Shah Medical Institute and Research Centre

drtejash@gmail.com9427332100

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026