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Effect of Phototherapy on Blood flow to brain, gut, and Cardiac output in neonates

Determining the Hemodynamics of Brain, Heart, and Gut using Bedside Doppler Ultrasound in Neonates of Gestation equal and more than 25 Weeks Before and During Phototherapy: A Prospective Observational Study - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/10/074742
Enrollment
100
Registered
2024-10-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control Intervention1: NIL: NIL, it is a observational study and no active intervention involved

Sponsors

Dr Ranganatha A Devaranavadagi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All Neonates with gestational age of � 25 weeks requiring phototherapy as per NICE phototherapy guidelines in neonates between 24 weeks and 35 weeks and AAP 2022 phototherapy guidelines for neonates of gestation �35 weeks anytime in their hospital stay.

Exclusion criteria

Exclusion criteria: 1. In whom consent is denied. 2. Received phototherapy for less than 12 hours for any reasons. 3. Neonates with already established NEC, other surgical abdomen. 4. Neonates with Shock documented by the Blood pressure readings as per gestational age. 5. Neonates with hS-PDA documented by 2D ECHO. 6. Neonates requiring exchange transfusion for treatment of neonatal hyperbilirubinemia. 7. Neonates with Acute Encephalopathy, seizures and neurological deficit due to any cause. 8. Neonates with major Congenital anomalies and complex heart diseases.

Design outcomes

Primary

MeasureTime frame
1.To calculate MCA-PSV, EDV, and RI before and during phototherapy 2.To calculate cardiac output before and during phototherapy 3.To calculate SMA-PSV, EDV, and RI before and during phototherapy Timepoint: To do Ultrasound Doppler before starting Phototherapy and after 12 hours of starting phototherapy

Secondary

MeasureTime frame
1. Impact of phototherapy on hemodynamics of brain, heart, and gut.Timepoint: A Hemodynamics assessment will be done before starting phototherapy and 12 hours after starting phototherapy.

Countries

India

Contacts

Public ContactRanganatha Devaranavadagi

Manipal Hospital, Old Airport Road, Bangalore

venkatveena46@gmail.com9980135300

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 27, 2026