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To investigate Ketamines Ability to Stabilize Blood Pressure in ICU Patients with Severe Infections: A Study on Septic Shock Treatment

To Determine The Antivasoplegic Effect Of Intravenous Ketamine In Septic Shock In ICU Patients: A Prospective Comparative Trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/074729
Enrollment
100
Registered
2024-10-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I638- Other cerebral infarction

Interventions

Intervention1: blood sample on day 1,3,5 for assessing IL-6 level and vasopressor requirements. We will follow-up the patient and noted total no days of ICU stay and mortality ,if any with in 28 days.

Sponsors

Intensive Care Unit
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 20-50 years old patients admitted in ICU with septic shock.

Exclusion criteria

Exclusion criteria: presence of shock other than septic shock, Pregnancy, Allergic to ketamine, Increased ICP, APACHE more than 25, Patient expired in 24hrs

Design outcomes

Primary

MeasureTime frame
Effect of ketamine on antivasoplegic effect by measuring interleukin 6 levelTimepoint: day 1 and day 5 of starting ketamine infusion—

Secondary

MeasureTime frame
Total vasopressor requirement Duration of vasopressor use ICU length of stay 28days mortality Effect on SOFAscore Timepoint: 28th day—

Countries

India

Contacts

Public ContactProf Zia Arshad

King Georges Medical University Lucknow

ziaarshad13@gmail.com9415722226

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026