Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Capsule Gabapentin 1200mg: Patient will be receiving Capsule Gabapentin 1200mg orally,one hour before surgery.
Control Intervention1: Capsule Pregabalin 300mg: Patient will be receiving
Sponsors
Dr Divya P
Eligibility
Inclusion criteria
Inclusion criteria: 1)Patient giving consent to participate in study 2)Patient undergoing lower limb surgeries 3)Age group between 18 to 60 years. 4)Both male and females 5)American Society of Anaesthesiologists grade 1 & 2
Exclusion criteria
Exclusion criteria: 1)Patient refusal 2)History of allergy to gabapentin and pregabalin 3)History of drug and alcohol abuse 4)History of chronic pain and chronic intake of analgesics 5)History of epilepsy and other neurological disorders 6)Patients who have been prescribed pregabalin or gabapentin for other indications 7)Pregnancy and breast feeding mothers 8) Liver and renal disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preemtive Pregabalin 300mg is expected to be more effective in prolongation of postoperative analgesia after spinal anaesthesia without altering the intraoperative hemodynamics.Timepoint: These outcomes are based on observations made after giving oral capsule one hour before spinal anaesthesia to 24 hour postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected stable hemodynamic profile and lesser side effects with Capsule Pregabalin 300mg.Timepoint: These outcomes are based on observations made after giving oral capsule one hour before spinal anaesthesia to 24 hour postopreratively. | — |
Countries
India
Contacts
Public ContactDr Preeti Goyal
Gajra Raja Medical College,Gwalior,Madhya Pradesh.
Outcome results
None listed