Toxicities and outcomes of radiation treatment administered to patients with cervical cancer at different times of a day

Effect of timing of radiotherapy In cervical cancer patients & its outcomes (E-TRICO) - A prospective randomised study - E-TRICO

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/074627

Enrollment

288

Registered

2024-10-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C53- Malignant neoplasm of cervix uteri

Interventions

Intervention1: Morning radiotherapy: Patients will receive at least 80% of their radiation treatment in the morning from 9AM to 11AM. Intervention is the timing at which we give radiation. Radiation w

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with ECOG performance status 0 to 2 2. Histopathologically confirmed carcinoma of uterine cervix. 3. FIGO stage IA, IB, IIA, IIB, IIIA, IIIB, IIIC 4. Patients who have given approved informed consent

Exclusion criteria

Exclusion criteria: 1. Patients who have received prior radiation to pelvis. 2. Pregnant and lactating women 3. Clinically significant diseases (Second primary tumour, severe infection, acute & chronic intestinal diseases, psychiatric illnesses, systemic immune diseases) 4. ECOG performance score: 3-4

Design outcomes

Primary

Measure	Time frame
To assess acute gastrointestinal and haematological toxicitiesTimepoint: Weekly once for six weeks from start of radiotherapy	—

Secondary

Measure	Time frame
To assess the tumour responseTimepoint: three months after completion of radiotherapy	—

Countries

India

Contacts

Public ContactCherwin Venati

SVIMS

cherwinvenati.97@gmail.com8331966436

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026