Comparing the effect of the drugs Levobupivacaine with Fentanyl versus Levobupivacaine with Demedetomidine in patients undergoing caesarean section under spinal anaesthesia

Efficacy of intrathecal Levobupivacaine with Fentanyl vs Levobupivacaine with Dexmedetomidine in patients undergoing LSCS: A prospective hospital based study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/074603

Enrollment

Registered

2024-10-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: Levobupivacaine with fentanyl: Patient receiving intrathecal hyperbaric levobupivacaine of 2.1 ml plus 25mcg(0.5ml) of fentanyl a total of 2.6ml Control Intervention1: Levobupivacine w

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2 Age between 18 to 40 years Height 150 TO 175 cms Weight 45 TO 80 kg

Exclusion criteria

Exclusion criteria: Coagulation disorders Foetal distress Patients with gestational hypertension Patient refusal

Design outcomes

Primary

Measure	Time frame
To compare the onset, duration of sensory and motor block and requirement of rescue analgesia for patients undergoing caesarean section under spinal anaesthesia with intrathecal fentanyl or dexmedetomidine with levobupivacine(H)Timepoint: 0 min, 1 min, 2 mins and after 4 to 6 hrs	—

Secondary

Measure	Time frame
To compare the haemodynamic parameters such as heart rate, non-invasive blood pressure, SpO2 between both the drugsTimepoint: Baseline (0 mins), 1 mins, 3 mins, 5 mins, 10 mins, 15 mins,20 mins,25 mins,30 mins,35 mins,40 mins,45 mins,50 mins,55 mins,60 mins	—

Countries

India

Contacts

Public ContactAddhavan R S

Jawaharlal Nehru Medical College

kedareshvara@gmail.com9886375154

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026