Health Condition 1: F332- Major depressive disorder, recurrent severe without psychotic features Health Condition 2: F331- Major depressive disorder, recurrent, moderate Health Condition 3: F321- Major depressive disorder, singleepisode, moderate Health Condition 4: F322- Major depressive disorder, singleepisode, severe without psychotic features
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Provision of signed and dated informed consent form 2. Clients diagnosed according to ICD-11 criteria for : · 6A70.1 Single Episode Depressive Disorder, Moderate, without psychotic symptoms · 6A70.3 Single Episode Depressive Disorder, Severe, without psychotic symptoms · A71.1 Recurrent Depressive Disorder, Current Episode Moderate, without psychotic symptoms · 6A71.3 Recurrent Depressive Disorder, Current Episode Severe, without psychotic symptoms 3. Age 18 to 50 years 4. Attend AIIMS Bhopal Psychiatry OPD 5. A score of 10 or above on the Patient Health Questionnaire 9 (PHQ-9) 6. Educated at least till 10th standard 7. Participants who are non responders of escitalopram
Exclusion criteria
Exclusion criteria: 1.Women who are pregnant or are breastfeeding or lactating 2. Participants with a history of organicity, epilepsy, or other neurological deficits. 3. Participants with a history of intellectual disability, psychosis, including schizophrenia spectrum disorders or bipolar disorder. 4. Participants planning to move out of the study area during the follow-up period. 5. Participants who do not speak either English or Hindi. 6. Participants who are undergoing psychotherapy for depression at the time of recruitment. 7. Participants at imminent risk for suicide. 8. Participants who have documented non-response to fluoxetine in current or past episodes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Illness Severity of Depression using PHQ-9 score. A score less than 10 will show change in illness severityTimepoint: Baseline, 4 weeks, 10 weeks, 1 month post intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in Wellbeing using Mental Health Continuum scoreTimepoint: Baseline, 10 weeks | — |
Countries
India
Contacts
AIIMS Bhopal