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Intravenous versus intranasal dexmedetomidine for suppression of stress response to laryngoscopy and intubation

Comparison of intravenous and intranasal dexmedetomidine for attenuation of stress response to laryngoscopy and intubation - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/10/074566
Enrollment
74
Registered
2024-10-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous and intranasal dexmedetomidine administration: Administration of intravenous dexmedetomidine 0.5 microgram per kg administration over 10 minutes, 10 minutes prior to inducti

Sponsors

Dr Ratna Saikia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 patients posted for elective surgery under general anesthesia with endotracheal intubation

Exclusion criteria

Exclusion criteria: emergency surgery, allergy to dexmedetomidine, heart rate less than 60 beats, heart block

Design outcomes

Primary

MeasureTime frame
Heart rate, systolic and diastolic blood pressure, mean arterial pressureTimepoint: Baseline,induction,intubation and every minute there after till ten minutes—

Secondary

MeasureTime frame
Monitor for hypotension, bradycardia, respiratory depressionTimepoint: From baseline until ten minutes of drug administration—

Countries

India

Contacts

Public ContactDeepak R

ESIC medical college & PGIMSR, Rajajinagar, Bangalore

deepakrkarnataka@gmail.com8088917782

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026