A Comparison of 2 medicine for postoperative pain relief

Comparative evaluation of intraperitoneal instillation of bupivacaine with magnesium sulphate versus bupivacaine with dexmedetomidine for post operative relief after laparoscopic cholecystectomy - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/10/074565

Enrollment

116

Registered

2024-10-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K80- Cholelithiasis Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Intraperitoneal instillation: Drug is instilled intraperitoneally in all the participants of the study. We observe patient for 24 hours post operatively Control Intervention1: Inj. Bupi

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 1 And 2 Age 18-65 Yrs Patients Undergoing Elective Laparoscopic Cholecystectomy surgery Patients With Informed Consent

Exclusion criteria

Exclusion criteria: Patients With ASA Grade 3 And 4 Known Allergy Or Hypersensitivity To Local Anaesthetic Drug Pregnancy, Patients With Asthma Or Chronic Lung Disease, Patients With Heart Disease, Patients With Renal Failure And Dialysis Patient Refusal

Design outcomes

Primary

Measure	Time frame
To evaluate and compare the efficacy and the quality of analgesia. Timepoint: Postoperatively pain will be assessed at different time intervals for initial 24 hrs	—

Secondary

Measure	Time frame
Assess hemodynamic changesTimepoint: Patient to be assessed for 24 hours post operatively at different time intervals;Complications if anyTimepoint: Patient to be assessed for 24 hours post operatively;Timing of requiring first dose of rescue analgesicTimepoint: Patient to be assessed for 24 hours post operatively;Total analgesic consumption in 24 hoursTimepoint: Patient to be assessed for 24 hours post operatively	—

Measure

Time frame

Assess hemodynamic changesTimepoint: Patient to be assessed for 24 hours post operatively at different time intervals;Complications if anyTimepoint: Patient to be assessed for 24 hours post operatively;Timing of requiring first dose of rescue analgesicTimepoint: Patient to be assessed for 24 hours post operatively;Total analgesic consumption in 24 hoursTimepoint: Patient to be assessed for 24 hours post operatively

—

Countries

India

Contacts

Public ContactDr Aditi Raj Singh

Lala Lajpat Rai Memorial Medical College Meerut

drsubhashllrm@gmail.com9837056949

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026