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Henna gel for the prevention of capecitabine-induced hand-foot syndrome in Cancer patients

Formulation and evaluation of topical preparation of Lawsonia inermis L. (Lythraceae) for the prevention of capecitabine induced hand-foot syndrome in Cancer patients - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/074530
Enrollment
180
Registered
2024-09-30
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site Health Condition 2: C189- Malignant neoplasm of colon, unspecified Health Condition 3: C20- Malignant neoplasm of rectum Health Condition 4: C169- Malignant neoplasm of stomach, unspecified

Interventions

Intervention1: Topical Henna Gel: Two fingertip unit of topical preparation will be applied on the soles and one fingertip unit on the palms from the first day of chemotherapy with capecitabine and co

Sponsors

JIPMER Intramural Resarch Fund
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of both gender older than 18 years. Patients attending Regional Cancer Centre, JIPMER who are diagnosed with cancer (breast cancer, Colorectal cancer and stomach cancer). Patients who are planned for capecitabine based chemotherapy regimen (1000-1250mg/m2 twice daily).

Exclusion criteria

Exclusion criteria: Patients who received capecitabine previously. Patients with pre-existing peripheral neuropathy and other dermatological disorders Patients who are on low dose capecitabine regimen (less than 1000mg per m2 twice daily).

Design outcomes

Primary

MeasureTime frame
The effect of topical henna preparation on the prevention of capecitabine induced hand foot syndrome in cancer patients.Timepoint: Every three weeks for nine weeks

Secondary

MeasureTime frame
The adverse reactions of topical preparation of henna in cancer patients with capecitabine induced hand foot syndrome.Timepoint: Every three weeks for nine weeks;The time taken for the appearance of capecitabine induced hand foot syndrome in cancer patients.Timepoint: Every three weeks for nine weeks

Countries

India

Contacts

Public ContactB Bhanupriya

JIPMER

drjayanthi2008@gmail.com9442395291

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026