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Role of early recognition of electrolyte and lactate imbalances and treatment with intravenous fluids intraoperatively to determine its effect on postoperative outcome of neurosurgery patients.

Role of early diagnosis and fluid management in perioperative electrolyte imbalances on outcome of postoperative neurosurgery patients– A Prospective Observational Study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/074514
Enrollment
400
Registered
2024-09-27
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: A preoperative arterial line and serial intraoperative ABG analysis: Arterial line will be taken with strict aseptic precautions by an experienced anesthesiologist. A baseline ABG is do

Sponsors

TNMC & BYL Nair Ch Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients above 18 years of age. 2. Patients undergoing elective craniotomy for Space Occupying Lesion (Infective, malignant, metastasis) 3. Patients undergoing emergency craniotomy for Traumatic Brain Injury (TBI)

Exclusion criteria

Exclusion criteria: 1. Patients having preoperative deranged renal function. 2. Patients with preoperative metabolic disturbances secondary to other causes.

Design outcomes

Primary

MeasureTime frame
1.To determine the occurrence of electrolyte imbalances such as Hyponatremia, Hypernatremia in adult patients undergoing elective craniotomy. 2.To determine the electrolyte imbalances such as hyponatremia and hypernatremia in all patients undergoing surgery for traumatic brain injury. 3.To determine the perioperative changes in lactate levels in all patients undergoing both elective and emergency craniotomy. Timepoint: Blood gas, lactate and electrolytes are measured and following time points. Preoperative, After Skin incision, After Craniotomy, During Skin closure, Post extubation if performed, POD at 6hrs, 12 hrs, 24hrs, 48 hrs, 72 hrs and POD 7

Secondary

MeasureTime frame
To study the impact of early diagnosis of electrolyte imbalances intraoperatively with appropriate fluid management based on electrolyte imbalances in the postoperative prognosis of the patient.Timepoint: POD 0, POD 1, POD 2, POD 3, POD 7

Countries

India

Contacts

Public ContactDr Sona Dave

TNMC, BYL Nair Ch. Hospital

sonadave@gmail.com9820067731

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026