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Changes in regional brain oxygen levels blood flow velocity in brain and lung function tests in patients undergoing deep brain stimulation surgery A prospective observational study

Perioperative changes in regional cerebral oxygenation cerebral blood flow velocity and pulmonary function tests in patients undergoing deep brain stimulation A Prospective Observational study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/09/074491
Enrollment
40
Registered
2024-09-27
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G20- Parkinsons disease

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES NIMHANS BENGALURU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients between 18-70 years of age undergoing DBS surgery. 2. ASA PS 1-3

Exclusion criteria

Exclusion criteria: 1. Known respiratory pathology 2. ICSOL or head injury in the past 3. Known cardiac failure 4. Refusal of consent

Design outcomes

Primary

MeasureTime frame
• The comparison of rSO2 (regionalcerebral oxygenation) changes during the DBS electrode placement, stimulation and after activation.Timepoint: • rSO2 (regional cerebral oxygenation) values at baseline, intraoperatively during the DBS electrode placement & stimulation, 24 hours before and 24 hours after activation of battery

Secondary

MeasureTime frame
• To compare the changes in middle cerebral artery velocity before electrode insertion & after insertion & activation of the electrode. • To compare the change in rSO2 to the change in the MDS-UPDRS scale after DBS. • To compare the change in pulmonary function test before electrode insertion, after insertion & activation of electrode. Timepoint: Baseline, 24 hours before & 24 hours after activation of battery

Countries

India

Contacts

Public ContactMADHUSUDAN REDDY

NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES (NIMHANS) BENGALURU

krmsr2000@yahoo.com9880103088

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026