Health Condition 1: M800- Age-related osteoporosis with current pathological fracture
Conditions
Interventions
Intervention1: Daily subcutaneous 20 micro gm Teriparatide Injection for 3 months: Patients falling in the intervention group will receive daily subcutaneous 20 micro gm Teriparatide Injection for 3 m
Sponsors
Research Cell, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow
Eligibility
Inclusion criteria
Inclusion criteria: Patients above the age of 50 years presenting with Intertrochanteric fractures at Apex Trauma Centre, SGPGIMS and having established osteoporosis (T-Score of hip less than -2.5 on DEXA scan) and having been managed by operative intervention by PFN-A2 (Proximal Femoral Nail- Antirotation 2) and willing to participate in the study
Exclusion criteria
Exclusion criteria: Age less than 50 years BMD not falling within the osteoporotic range (T score of hip more than -2.5) Patients that were managed conservatively due to comorbidities Patients having contraindication to Teriparatide injection (like hypercalcemia, hyperparathyroidism, metabolic bone disease other than osteoporosis) Patients having any other bony fracture in the ipsilateral limb Patients having pre-existing hip disease Previous history of having taken Teriparatide or bisphosphonates or calcitonin or any hormonal therapy for osteoporosis within one year Patients not willing to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fracture Union (based on RUSH (Radiographic Union Scale for Hip) score)Timepoint: 6, 12, 18 and 24 weeks. After that, they will be followed-up at 3 monthly intervals till 1 year. | — |
Secondary
| Measure | Time frame |
|---|---|
| Presence of any local or systemic complications, Change in Bone Mineral Density (BMD), Functional OutcomeTimepoint: 6, 12, 18 and 24 weeks. After that, they will be followed-up at 3 monthly intervals till 1 year. | — |
Countries
India
Contacts
Public ContactKUMAR KESHAV
Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow
Outcome results
None listed