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Immune markers and their association with genetic signatures among HIV/HPV coinfected women:A study from 2 tertiary care hospitals in Mumbai.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/09/074419
Enrollment
120
Registered
2024-09-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B20- Human immunodeficiency virus [HIV]disease Health Condition 2: N738- Other specified female pelvic inflammatory diseases

Interventions

Control Intervention1: NIL: NIL

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Sexually active women in the age group =18 years visiting the Integrated Counselling and Testing Centre (ICTC) for HIV testing.

Exclusion criteria

Exclusion criteria: 1.Women with history of any ongoing active infections e.g. TB or any other immunomodulatory disease. 2.Women currently on ART therapy, steroid treatment and pre-operative cases. 3.Women who are pregnant. 4.Women undergoing cryotherapy, Loop Electrosurgical Excision Procedure(LEEP), Chemo or radiotherapy.

Design outcomes

Primary

MeasureTime frame
1.Comparison of Systemic and Cervical immune expression 2.Influence of the specific HPV genotype and genetic signature on the immune markers during a coinfection. 3.Immunophenotype and cytokine profile of patients infect with HIV, HPV & having a HIV-HPV coinfection 4.Comparison of Systemic and Cervical immune expression Timepoint: As this is an observational study there are no defined time lines.

Secondary

MeasureTime frame
NATimepoint: NA

Countries

India

Contacts

Public ContactDr Jayanthi Shastri

COE in Research and Training in Infectious Diseases

coeimmunologynair@gmail.com0

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026