Effect of Vitamin D supplementation in patients with Dry Eye Disease.

Effect of Vitamin D supplementation on ocular surface and tear film parameters in patients with Dry Eye Disease. - NIL

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/074370

Enrollment

Registered

2024-09-25

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H048- Other disorders of lacrimal system

Interventions

Intervention1: Vitamin D along with Artificial tears: Oral Vitamin D 60,000 IU weekly for 8 weeks along with artificial tears. Control Intervention1: Artificial tears: Artificial tears alone given for

Eligibility

Inclusion criteria

Inclusion criteria: Patients meeting the criteria for Dry Eye Disease and with Vitamin D levels below 20 ng/mL

Exclusion criteria

Exclusion criteria: Patients who are already on vitamin D supplementation,patients on drugs which alter vitamin D metabolism,autoimmune diseases,history of intraocular surgery,corneal opacity,ocular injuries,contact lens users,corneal diseases like keratoconus or recurrent erosion syndromes,corneal surgery history,diabetes mellitus,thyroid disease patients.

Design outcomes

Primary

Measure	Time frame
To study the effect of Vitamin D supplementation on conjunctival impression cytology and tear film parameters. Timepoint: 8 weeks	—

Secondary

Measure	Time frame
Effect of Vitamin D supplementation on dry eye parameters which will include OSDI (Ocular Surface Disease Index) Score,SchirmerÃ¢â?¬â?¢s test 1 & 2,TBUT(Tear Breakup Time) & Meibography in two groups at the time of enrolment & after 8 weeks of intervention one being treated with artificial tears along with oral Vitamin D & the other group being treated with artificial tears alone.Timepoint: At the time of enrolment & after 8 weeks of intervention.	—

Measure

Time frame

Effect of Vitamin D supplementation on dry eye parameters which will include OSDI (Ocular Surface Disease Index) Score,SchirmerÃ¢â?¬â?¢s test 1 & 2,TBUT(Tear Breakup Time) & Meibography in two groups at the time of enrolment & after 8 weeks of intervention one being treated with artificial tears along with oral Vitamin D & the other group being treated with artificial tears alone.Timepoint: At the time of enrolment & after 8 weeks of intervention.

—

Countries

India

Contacts

Public ContactProfessor Adeeb Alam Khan

Institute of Ophthalmology,JNMCH,Aligarh Muslim University.

dradeebkhan@gmail.com9837252564

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026