Health Condition 1: F322- Major depressive disorder, singleepisode, severe without psychotic features
Conditions
Interventions
Intervention1: Constitutional Homoeopathic Medications, Medicine will be selected after case taking and individualization of each case: Potentised Homoeopathic Medications Selected Based on the Sympto
Sponsors
Dr. Sreya N
Eligibility
Inclusion criteria
Inclusion criteria: 1. Case Definition - The following signs and symptoms if present nearly every day for at least 2 weeks or more: Persistent sad, anxious, or “empty ? mood Feelings of hopelessness, pessimism Feelings of guilt, worthlessness, helplessness Loss of interest or pleasure in hobbies and activities Decreased energy, fatigue, being “slowed down ? Difficulty concentrating, remembering, making decisions Difficulty sleeping, early-morning awakening, or oversleeping Appetite and/or unwanted weight changes Thoughts of death or suicide; suicide attempts Restlessness, irritability Persistent physical symptoms, such as muscle pain or headaches. 2. Patients assessed using both HDR and PHQ9 Scale with the values of HDR Scale Score - greater than or equal to 10 and less than or equal to 18. PHQ9 Scale Score- greater than or equal to 5 and less than or equal to 20. 3. Patients fulfilling scores of both scales simultaneously will only be considered. 4. Cases that fulfil the case definition along with assessment scores will only be included. 5. Patients irrespective of socio-economic status. 6. Patients already diagnosed with depression but not under any medications. 7. Patients with washout period of more than 6 months but satisfy case definition.
Exclusion criteria
Exclusion criteria: 1. Age group of below 18 years and above 30 years. 2. Patients not fulfilling the case definition. 3. Patients who do not satisfy the assessment scores or the scores are only valid in one of the scales used for assessment. 4. Patient already diagnosed and under treatment for depression. 5. Patient under anti-psycotic or anti-depressant drugs. 6. Patient who need emergency medical or surgical intervention. 7. Patients diagnosed with severe depression, depression associated with other medical conditions like cancer, bipolar disorders, anxiety and other unspecified mood disorders and depression with psychotic symptoms like hallucinations. 8. Patients with washout period less than 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To find the efficacy of Homoeopathic medications in the treatment of depression in early adulthood.Timepoint: Follow up every 2 weeks for a period of 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| To understand is there any clinical significance of homoeopathic medications in the treatment of depression in early adulthood.Timepoint: Follow up every 2 weeks for a period of 6 months. | — |
Countries
India
Contacts
Public ContactProf Dr Mrinal A Nerlekar
BVDU Homoeopathic Medical College, Department of Post Graduate and Research Centre
Outcome results
None listed