None listed
Conditions
Interventions
Intervention1: Preventive dental care: Dental caries is one of the most prevalent chronic diseases affecting both adults and children globally. Probiotics have emerged as a promising intervention for
Sponsors
Dr Dipanshu Kumar
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children aged 6 to 12 years with or without dental caries. 2. Participants must be in good general health as determined by a medical history and physical examination. 3. Parents or guardians must provide written informed consent, and children must provide assent.
Exclusion criteria
Exclusion criteria: Children who have taken antibiotics or probiotics within the past 4 weeks. Children with any chronic illness or condition that could affect oral health or saliva production Children with a history of allergies to probiotics or any components of the lozenges or gummies. Children who are unable to comply with the study protocol, including regular attendance for follow-up visits. Children with a history of chronic use of medications that may affect oral flora, such as long-term steroid therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change in the counts of Streptococcus mutans and Lactobacillus in salivaTimepoint: 1. Baseline 2. 1-hour post consumption 3. After 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The change in the pH and buffering capacity of saliva from baseline to 1-hour post consumption and after 7 days. 2. Adherence to and acceptability of the interventions, assessed through participant and caregiver reports and pill counts.Timepoint: 1. Baseline 2. 1-hour post consumption 3. After 7 days | — |
Countries
India
Contacts
Public ContactDr Dipanshu Kumar
Department of Dentistry, AIIMS, Gorakhpur
Outcome results
None listed