Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Needle Electromyographic Guidance of Botulinum toxin injection: The subjects will undergo a Single session (30 minutes) of Botulinum Toxin injection for upper face dynamic wrinkles guid
Sponsors
NEIGRIHMS Hospital Shillong
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects with Upper face wrinkles who want correction 2. Subjects with dominant glabellar lines with an angry facial expression even in a relaxed state. These subjects want to eliminate the angry facial expression
Exclusion criteria
Exclusion criteria: 1. Co-morbidities like hypertension, diabetes mellitus, collagen vascular disorders and autoimmune disorders. 2. Subjects with muscular dystrophy syndrome 3. Pregnant and lactating mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Dermatology Life Quality Index Score System. 2. EMG Readings to look for the efficacy of the Botulinum toxin: A) RMS : Root Mean square of bin of contraction, with 100ms envelope window B) MVIC: Maximum voluntary isometric contraction C) SNR:Signal to Noise ratio D) Integral absolute value : Time domain assessement E) MDF:Median power frequency F) Inertial measurement: Accelerometer, Gyrometer.Timepoint: baseline-at the time of intervention. At 2 weeks, 3 months, and 6 months after the procedure. | — |
Secondary
| Measure | Time frame |
|---|---|
| The complications are noted in the subjects undergoing these procedures. The compications are ptosis of the eyelid or eyebrow, eyebrow asymmetry, diplopia, lagophthalmos, palpebral ectropion, & prominence of the palpebral bags.Timepoint: At 2 weeks, 3 months & 6 months following the procedure. | — |
Countries
India
Contacts
Public ContactBadamutlang Dympep
NEIGRIHMS
Outcome results
None listed