Health Condition 1: P369- Bacterial sepsis of newborn, unspecified Health Condition 2: P071- Other low birth weight newborn
Conditions
Interventions
Intervention1: Immediate Kangaroo mother care (iKMC): 1. iKMC is immediate and continuous KMC, which means KMC will be started soon after birth (within 12 hrs of life) and to be given continuously - f
Sponsors
All India Institute of Medical Sciences, New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: All live low birth weight (1000-1799 g) neonates admitted to the study hospitals, irrespective of place of birth, in whom KMC can be initiated within 12 hours of life.
Exclusion criteria
Exclusion criteria: Neonates born to mothers who are unwilling to provide consent or whose mother is sick and unlikely to be able to provide KMC within the first three days after birth, Neonates who require intubation and mechanical ventilation or inotropes for shock within the first 12 hours of life, Neonates born to mothers younger than 18 years of age, Triplets or higher-order births, Major congenital malformation that interferes with the intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of all-cause neonatal mortality and/or culture-positive sepsis among neonates with birth weights of 1000-1799 g and admitted to level-2 units of the district hospitals until discharge or 28 days of life, whichever is earlierTimepoint: Until discharge or 28 days of life, whichever is earlier | — |
Secondary
| Measure | Time frame |
|---|---|
| Early and late neonatal mortality rateTimepoint: 7 and 28 days of life;Incidence of early-onset culture positive sepsisTimepoint: 72 hours of life;Incidence of late-onset culture-positive sepsisTimepoint: 28 days;Incidence of clinical sepsisTimepoint: 28 days;Pathogen profile and antimicrobial resistance pattern in neonates with culture-positive sepsisTimepoint: 28 days;Exclusive expressed breast milk feeding or exclusive direct breastfeedingTimepoint: At discharge;Skin and gut colonization of the neonatesTimepoint: Day 3 and day 7 | — |
Countries
India
Contacts
Public ContactM Jeeva Sankar
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed