A Comparative Analysis of Satranidazole and Aloe Vera Gels in Local Drug Delivery for Chronic Periodontitis: A Randomized, Single-Blind Study

Comparative evaluation of Satranidazole gel and Aloe-vera gel through local drug delivery system in the treatment of Chronic Periodontitis: A Randomized, Single-blind, Parallel group study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/074265

Enrollment

Registered

2024-09-24

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Satranidazole: Satranidazole tablet 300mg dispersed to formulate a gel as a local drug delivery administration for a total duration of intervention as 1 month. Control Intervention1: Al

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with mild to moderate chronic periodontitis. 2. Pocket depth of 4-6mm 3. No history of antibiotic or periodontal therapy in the previous 6 months

Exclusion criteria

Exclusion criteria: 1. Patients taking medications that could affect their periodontal health 2. Known allergy to herbal products/medications 3. Receiving systemic antimicrobial therapy 4. Patients with aggressive periodontitis 5. Patients with adverse habits 6. Pregnant, or nursing females

Design outcomes

Primary

Measure	Time frame
Probing pocket depth, bleeding indexTimepoint: Baseline & 4 weeks	—

Secondary

Measure	Time frame
gingival index and plaque indexTimepoint: baseline and one-month	—

Countries

India

Contacts

Public ContactDr Aadarsh Vikram Dhan

Chhattisgarh Dental College and Research Institute

hirojbagde8@gmail.com9766105900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026