None listed
Conditions
Interventions
Intervention1: Volunteer will be subjected to trendelenburg 45 degree: NPi will be measured at baseline and after subjecting the volunteer to trendelenburg position 45 degree and after bringing back t
Sponsors
Sanjay Gandhi Post Graduate Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Adult healthy volunteer who consent to participate in the study
Exclusion criteria
Exclusion criteria: Volunteer Refusal BMI more 25 KG per M2 Any eye disorder or history of glaucoma Any cardiac, pulmonary, hepatic or renal disease Bradycardia defined as less than 45 beats per minute Hypotension defined as SBP less than 90 mm Hg Hypertension defined as SBP more than 140 mm Hg IVC diameter less than 1.5 cm and more than 2 cm Positive Pregnancy test Any known case of intracranial pathology like Tumour/vascular or infective pathology History of stroke Ischemic/ haemorragic Any recent use of eye drop affecting the pupillary size Active case of myasthenia graves or similar neurological abnormalities Horner syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary aim of the study will be to evaluate and compare the changes in NPi after 30 minutes of subjecting one group of volunteer from supine to 25 degree and another group from supine to 45 degree trendelenburg positionTimepoint: NPi will be measured at baseline after that at 30 minutes and after 30 minutes of bringing to the neutral position. That is at TO(BASELINE)-T1(AT 30 MINUTES)-T2 (AT 60 MINUTES FROM BASELINE) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Observation of any symptoms like headache, diplopia, nausea and vomiting, any transient neurological sign or symptoms. 2.Facial swelling or corneal oedema, change of voice, during the procedure till 24 hours.Timepoint: Baseline to 24 hours | — |
Countries
India
Contacts
Public ContactPrateek Singh
Sanjay Gandhi Post Graduate Institute of Medical Sciences Lucknow
Outcome results
None listed